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 JS
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Detailed Insider History for:
OPKO HEALTH INC: OPK
Price: 11/21/25 52-Wk
High		 52-Wk
Low		 Mkt Cap (mm) Shrs Out (mm) 3-Mth Ave
Vol (m)		 Ind. Yield Short Int
% Float		 Inst. Owned Insider Owned
$1.32 $2.04 $1.11 $1,048 768 2,298 0.0% 7.5% 26.14% 48.63%
Exch Sector Industry Sub-Industry
NasdaqGS Manufacturing Chemicals And Allied Products Pharmaceutical Preparations
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#
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Insider Statistics
T N H M S
Filer Name
Insider Title
Trans Type
Dollar Value
Shares Traded
Trans Date From
Trans Date To
Trans Price From
Trans Price To
Total Holdings
Delta % Owned
Owned
Other Info
Input Date
1
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$768,807
580,000
---
11/21/25
$1.30
$1.34
216,706,448
0.3
I
---
11/21/25 - 5:07:09 pm
2
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$771,328
580,000
---
11/20/25
$1.32
$1.35
216,126,448
0.3
I
---
11/20/25 - 6:10:53 pm
3
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$759,115
580,000
---
11/19/25
$1.28
$1.32
215,546,448
0.3
I
---
11/19/25 - 5:02:21 pm
4
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$678,906
533,300
---
11/18/25
$1.25
$1.29
214,966,448
0.2
I
---
11/18/25 - 5:18:12 pm
5
    
 
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
JB
$58,842
46,700
---
11/18/25
---
$1.26
214,549,776
0.0
I
---
11/18/25 - 5:18:12 pm
6
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$213,435
150,000
---
10/31/25
---
$1.42
214,386,448
0.1
I
---
10/31/25 - 5:15:41 pm
7
    
 
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
JS
---
440,000
---
8/18/25
---
---
214,236,448
-0.2
I
---
8/19/25 - 4:08:47 pm
8
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$891,000
675,000
---
8/8/25
---
$1.32
214,676,448
0.3
I
---
8/8/25 - 4:56:12 pm
9
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$169,713
125,000
---
4/10/25
---
$1.36
214,001,440
0.1
I
---
4/10/25 - 5:07:15 pm
10
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$184,650
125,000
---
4/8/25
---
$1.48
213,876,448
0.1
I
---
4/8/25 - 5:34:21 pm
11
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$164,850
100,000
---
4/1/25
---
$1.65
213,751,456
0.0
I
---
4/1/25 - 5:21:45 pm
12
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$254,385
150,000
---
3/28/25
---
$1.70
213,651,456
0.1
I
---
3/28/25 - 5:22:09 pm
13
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$347,820
200,000
---
3/17/25
---
$1.74
213,501,440
0.1
I
---
3/17/25 - 5:27:48 pm
14
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$115,312
67,434
---
2/28/25
---
$1.71
213,301,440
0.0
I
---
2/28/25 - 7:34:01 pm
15
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$70,060
47,537
---
1/28/25
---
$1.47
213,234,016
0.0
I
---
1/28/25 - 5:40:23 pm
16
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$740,850
500,000
---
1/15/25
---
$1.48
213,036,480
0.2
I
---
1/15/25 - 5:18:44 pm
17
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$199,375
125,000
---
12/13/24
---
$1.60
212,536,480
0.1
I
---
12/13/24 - 5:04:40 pm
18
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$781,050
500,000
---
12/11/24
---
$1.56
212,411,472
0.2
I
---
12/11/24 - 5:21:28 pm
19
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$305,376
199,072
---
11/29/24
---
$1.53
211,911,472
0.1
I
---
11/29/24 - 3:20:16 pm
20
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$159,000
100,000
---
11/22/24
---
$1.59
211,712,400
0.0
I
---
11/22/24 - 5:17:09 pm
21
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$161,980
100,000
---
11/14/24
---
$1.62
211,612,400
0.0
I
---
11/14/24 - 5:51:36 pm
22
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$421,535
280,183
---
11/8/24
---
$1.50
211,512,400
0.1
I
A
11/20/24 - 7:21:31 pm
23
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$421,535
280,183
---
11/8/24
---
$1.50
211,512,400
0.1
I
---
11/8/24 - 5:40:44 pm
24
    
 
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
JB
---
500,000
---
7/24/24
---
---
3,568,951
16.3
D
R
7/26/24 - 7:21:32 pm
25
    
 
HSIAO JANE PH D
VCB,CTO,DIR
JB
---
500,000
---
7/24/24
---
---
28,499,880
1.8
D
R
7/26/24 - 7:18:18 pm
26
    
 
LOGAL ADAM
VP,CFO
JB
---
437,500
---
7/24/24
---
---
616,662
244.2
D
R
7/26/24 - 7:15:29 pm
27
    
 
RUBIN STEVEN D
VP,DIR
JB
---
437,500
---
7/24/24
---
---
6,625,232
7.1
D
R
7/26/24 - 7:11:51 pm
28
    
 
ZERHOUNI ELIAS A
VCB,PR,DIR
JB
---
500,000
---
7/24/24
---
---
589,600
558.0
D
R
7/26/24 - 7:08:16 pm
29
    
 
NABEL GARY J
DIR
JB
---
437,500
---
7/24/24
---
---
700,579
166.3
D
R
7/26/24 - 7:05:39 pm
30
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$126,937
100,000
---
5/23/24
---
$1.26
211,232,224
0.0
I
---
5/23/24 - 8:04:15 pm
31
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$211,195
163,997
---
5/17/24
---
$1.29
211,132,224
0.1
I
---
5/17/24 - 5:31:27 pm
32
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$437,100
500,000
---
3/18/24
---
$0.87
210,968,224
0.2
I
---
3/18/24 - 4:45:08 pm
33
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$444,300
500,000
---
3/14/24
---
$0.89
210,468,224
0.2
I
---
3/14/24 - 5:00:41 pm
34
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$463,750
500,000
---
3/13/24
---
$0.93
209,968,224
0.2
I
---
3/13/24 - 4:44:17 pm
35
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$559,380
600,000
---
3/12/24
---
$0.93
209,468,224
0.3
I
---
3/12/24 - 5:27:29 pm
36
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$496,150
500,000
---
2/28/24
---
$0.99
208,868,224
0.2
I
---
2/28/24 - 5:31:35 pm
37
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$991,700
1,000,000
---
2/21/24
---
$0.99
208,368,224
0.5
I
---
2/21/24 - 5:10:47 pm
38
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$1,462,800
1,500,000
---
2/7/24
---
$0.98
207,368,224
0.7
I
---
2/7/24 - 5:09:25 pm
39
1y
1
100%
52%
5
KRASNO RICHARD M
DIR
B
$29,838
30,000
---
1/29/24
---
$0.99
103,333
40.9
I
---
1/29/24 - 3:30:14 pm
40
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$488,650
500,000
---
1/19/24
---
$0.98
205,868,224
0.2
I
---
1/19/24 - 4:54:00 pm
41
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$386,200
400,000
---
1/18/24
---
$0.97
205,368,224
0.2
I
---
1/18/24 - 5:06:22 pm
42
1y
34
44%
9%
6
HSIAO JANE PH D
VCB,CTO,DIR
B
$142,500
150,000
---
1/17/24
---
$0.95
27,999,880
0.5
D
---
1/17/24 - 5:09:48 pm
43
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$954,300
1,000,000
---
1/16/24
---
$0.95
204,968,224
0.5
I
---
1/16/24 - 5:03:01 pm
44
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$480,379
511,531
---
1/11/24
---
$0.94
203,968,224
0.3
I
---
1/11/24 - 5:15:36 pm
45
    
 
NABEL GARY J
DIR
B
$200,427
216,184
---
1/8/24
$0.92
$0.93
351,442
159.8
I
---
1/10/24 - 5:56:45 pm
46
1y
34
44%
9%
6
HSIAO JANE PH D
VCB,CTO,DIR
B
$130,899
150,010
---
1/5/24
---
$0.87
27,849,880
0.5
D
---
1/8/24 - 9:10:34 am
47
1y
1531
59%
23%
19
FROST PHILLIP MD ET AL
CEO,CB,DIR,BO
B
$1,344,600
1,500,000
---
1/5/24
---
$0.90
203,456,688
0.7
I
---
1/8/24 - 8:54:32 am
48
1y
2
50%
15%
2
ZERHOUNI ELIAS A
VCB,PR,DIR
B
$514,093
550,300
---
1/5/24
$0.87
$0.94
20,327,814
2.8
I
---
1/5/24 - 5:26:26 pm
49
1y
20
50%
3%
2
PAGANELLI JOHN A
DIR
B
$22,080
25,000
---
1/5/24
---
$0.88
384,340
7.0
D
---
1/5/24 - 4:00:01 pm
50
1y
26
27%
-8%
9
RUBIN STEVEN D
VP,DIR
B
$8,669
10,000
---
1/5/24
---
$0.87
6,187,732
0.2
D
---
1/5/24 - 1:39:36 pm
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