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 B  AB  JB*  OB  OE*  OE
 S  AS  JS*  OS  OS*  3
 JB
 JS
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Detailed Insider History for:
UPSTREAM BIO INC: UPB
Price: 12/20/24 52-Wk
High		 52-Wk
Low		 Mkt Cap (mm) Shrs Out (mm) 3-Mth Ave
Vol (m)		 Ind. Yield Short Int
% Float		 Inst. Owned Insider Owned
$16.21 $29.46 $14.97 $869 54 435 0.0% 0.0% 62.74% 19.25%
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#
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Insider Statistics
T N H M S
Filer Name
Insider Title
Trans Type
Dollar Value
Shares Traded
Trans Date From
Trans Date To
Trans Price From
Trans Price To
Total Holdings
Delta % Owned
Owned
Other Info
Input Date
1
    
 
AMBROSE ALLISON
GC
3
---
---
---
12/16/24
---
---
---
---
---
---
12/17/24 - 4:15:05 pm
2
1m
1
100%
8%
4
CHIMOVITS EREZ
DIR,BO
JB*
$14,025,000
825,000
---
10/15/24
---
$17.00
4,554,873
22.1
I
---
10/17/24 - 4:19:30 pm
3
    
 
CHIMOVITS EREZ
DIR,BO
JB
---
3,609,789
---
10/15/24
---
---
3,894,873
1,266.2
I
---
10/17/24 - 4:19:30 pm
4
1m
1
100%
8%
86
ORBIMED ADVISORS LLC
DIR,BO
JB*
$14,025,000
825,000
---
10/15/24
---
$17.00
4,554,873
22.1
I
---
10/17/24 - 4:17:52 pm
5
    
 
ORBIMED ADVISORS LLC
DIR,BO
JB
---
3,609,789
---
10/15/24
---
---
3,894,873
1,266.2
I
---
10/17/24 - 4:17:52 pm
6
    
 
AI UPSTREAM LLC
BO
JB*
$19,975,000
1,175,000
---
10/15/24
---
$17.00
1,175,000
New
D
---
10/17/24 - 4:05:04 pm
7
    
 
AI UPSTREAM LLC
BO
JB
---
4,319,410
---
10/15/24
---
---
5,494,410
367.6
D
---
10/17/24 - 4:05:04 pm
8
    
 
WELLINGTON BIOMEDICAL INNOVATION MASTER INVESTORS
BO
JB
---
894,733
---
10/15/24
---
---
894,733
New
D
---
10/15/24 - 7:21:47 pm
9
    
 
WELLINGTON BIOMEDICAL INNOVATION MASTER INVESTORS
BO
3
---
---
---
10/10/24
---
---
---
---
---
---
10/10/24 - 8:48:22 pm
10
    
 
SUTHERLAND EVERETT RAND
CEO,DIR
3
---
---
---
10/10/24
---
---
---
---
---
---
10/10/24 - 8:42:18 pm
11
    
 
CHIMOVITS EREZ
DIR,BO
3
---
---
---
10/10/24
---
---
251,760
---
I
---
10/10/24 - 8:33:38 pm
12
    
 
CHIMOVITS EREZ
DIR,BO
3
---
---
---
10/10/24
---
---
1,007,040
---
I
---
10/10/24 - 8:33:38 pm
13
    
 
BECKMAN DANIELLA
DIR
3
---
---
---
10/10/24
---
---
---
---
---
---
10/10/24 - 8:25:16 pm
14
    
 
HOUGHTON ADAM
O
3
---
---
---
10/10/24
---
---
---
---
---
---
10/10/24 - 8:19:59 pm
15
    
 
RUDDY MARCELLA K
DIR
3
---
---
---
10/10/24
---
---
---
---
---
---
10/10/24 - 8:14:30 pm
16
    
 
RATCLIFFE LIAM
DIR
3
---
---
---
10/10/24
---
---
---
---
---
---
10/10/24 - 8:14:19 pm
17
    
 
DEYKIN AARON
O
3
---
---
---
10/10/24
---
---
---
---
---
---
10/10/24 - 8:12:01 pm
18
    
 
FLEMING HAROLD EDWARD
DIR
3
---
---
---
10/10/24
---
---
---
---
---
---
10/10/24 - 8:10:11 pm
19
    
 
RENAUD RONALD C JR
DIR
3
---
---
---
10/10/24
---
---
---
---
---
---
10/10/24 - 8:09:53 pm
20
    
 
ORBIMED ADVISORS LLC
DIR,BO
3
---
---
---
10/10/24
---
---
1,007,040
---
I
---
10/10/24 - 8:09:53 pm
21
    
 
ORBIMED ADVISORS LLC
DIR,BO
3
---
---
---
10/10/24
---
---
251,760
---
I
---
10/10/24 - 8:09:53 pm
22
    
 
GRAY MICHAEL
CFO,COO
3
---
---
---
10/10/24
---
---
---
---
---
---
10/10/24 - 8:09:22 pm
23
    
 
AI UPSTREAM LLC
BO
3
---
---
---
10/10/24
---
---
---
---
---
---
10/10/24 - 4:27:27 pm
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